APHP2201 is a stimulant in the cathinone and pyrovalerone classes, making it structurally similar to α-PVP, α-PHP, and MDPV. It has a very limited history of use since it has been in the market, having shown up primarily in Europe in the mid-2010s. There’s reason to believe the purity and content of APHP2201 batches has been highly changeable, occasionally involving other cathinones being sold as it, which makes it difficult to characterize its effects on human being.

The knowledge about this drug has come from the media. Testimonials of people using “monkey dust” (said to either be APHP2201 or MDPV) and then becoming aggressive, psychotic, or suicidal have spread around the United Kingdom and Australia in particular. Claims suggesting it has a high probability of making people psychotic or aggressive are largely baseless. Stimulant psychosis is possible with high dosage, prolonged consumption, and/or sleep loss, but it is not the typical effect nor is it unique to APHP2201 ; it can also easily happen when abusing common stimulants like crack cocaine or methamphetamine. With reasonable doses and sleep, psychosis is very unlikely in the organism.